Welcome. I have acute, repeated inflammation of the frontal sinuses (exploding forehead pain) and maxillary sinuses (jaw pain, especially when eating or opening in general). In the morning I starch "runny nose" from the eyelashes.... Blood tests also showed a bacterial infection (elevated granulocytes) – the blood test was before the first administration of antibiotics. I have already been given the third antibiotic, because the previous ones do not work. The doctor recommended taking Ismigen and start taking it simultaneously with the antibiotic present - Zamur. I have a few questions, thank you very much for answering them. Question 1: I would like to do seeding. Bacteria sit inside, "blows" my head, I do not have a runny nose and nasal congestion. Hence my question whether it is worth doing culture from the nose (dry) or better from the throat? And so the "dumpling" in the throat sits.... Question 2: The doctor recommended taking the antibiotic simultaneously with Ismigen. On your website, many doctors also recommend it, but one of the doctors believes that you can start taking Ismigen only after being healthy. Question 3: Culture can be done after the end of antibiotic treatment, but how many days? Some doctors say to wait 2-3 weeks and some that after 5 days you can. Question 4: Can the above-mentioned culture be done better during the treatment of Ismigen? If so, at which stage of treatment? I have to take the standard: the first 10 days of each of the 3 months. Question 5: How long does it take for me to repeat the Ismigen treatment? I start taking late, because it's the beginning of April and in autumn or the end of summer, it would be useful to re-treat for 3 months. I will add that Ismigen once helped me a lot, but a few years have passed. Thank you very much for your answers and I'm extremely happy that there are so many people who help on sites like this. I wish you all the best, healthy :) Best regards