Is it permissible to increase the dose of medication from the doses prescribed by the doctor, being self-aware and very broad knowledge of bipolar disorder combined with ADD, with which I live? Lamotrigine from 300mg divided into two doses for 400mg also podzione, Duloxetine from 60 to a maximum dose of 120mg, Bupropion temporarily from 300mg to 450, but I returned so the previous dose, Pregabalin, króea does not work properly (imperceptibly) in a dose of 75mg twice a day for a dose of 300mg or even higher than the maximum recommended i.e. 600 mg twice a day (then I feel its real effect. I will add that I am drug-resistant and I am affected mainly by depressive episodes, only sometimes hypomanic, and thanks to the drugs I have a very stable mood and I feel reallywell, almost normally on these doses of drugs. I still take intermittently methylphenidate - 20mg with immediate development and a capsule with slow action over a few hours in the morning and 20-40mg later, in the evening, when the effect drops significantly and is no longer almost noticeable (under the supervision of a doctor.