What interval should be kept between the use of ibuprofen and indomethacin?

There is no minimum time interval between ibuprofen and indomethacin in Metindol Retard. In general, concomitant use of substances belonging to non-steroidal anti-inflammatory drugs, which include both ibuprofen and indomethacin, should be avoided. This is associated with the risk of increased side effects, mainly related to gastrointestinal bleeding, during their simultaneous use. However, if the headache is severe and no improvement is observed about an hour after ibuprofen administration, you can take the medicine recommended by your doctor with indomethacin (Metindole Retard). Most likely, a single use of these drugs should not pose a health risk. I would like to point out, however, that this applies to exceptional situations and people who have not been diagnosed with ulcers or gastrointestinal bleeding in the past. We wrote more about whether taking several drugs can be dangerous in the following text: https://www.gdziepolek.pl/artykuly/czy-przyjmowanie-kilku-lekow-jednoczesnie-jest-bezpieczne Below are also links to track the availability, reservation or purchase and collection of said medicines at any pharmacy of your choice upon presentation of a prescription (in the case of prescription drugs, a prescription must be presented:- https://www.gdziepolek.pl/produkty/48706/metindol-retard-tabletki-o-przedluzonym-uwalnianiu/apteki, - https://www.gdziepolek.pl/produkty/105567/ibuprofen-aristo-tabletki-powlekane/aptek. You can read more about cluster headache in the text: https://www.gdziepolek.pl/artykuly/klasterowy-bol-glowy-jak-sie-nie-poddac