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Maria (Anonymous, 88.199.88.) Warszawa 17 months ago

Could increasing the dose of Asertin cause stomach problems?

Dear pharmacists! A month ago I increased the dose of Asertin that 100 to 150 mg. Since then, I observe loose stools 1 time per day and overflow in the abdomen, but generally well-being. However, from 3 days stools liquid, more frequent and more annoying. I'm torn from medication or not. I have not changed my diet, I feel good. Is it necessary to reduce the dose? But should we look for the cause elsewhere? How to help yourself at this time so that it does not affect the treatment with Asertin? Thanks in advance for your help.

3 answers, 1 subscriber

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Anna Lewandowska Pharmacist, Editor

5 days ago

To @Agata:

If your son gets up later (e.g. at 11-12 p.m.), you can postpone the first dose to that time.
The second dose is then best taken about 5-6 hours later (e.g. 4-5 p.m.).

Ideally, you should keep a constant interval between doses, about 5-6 hours. If the rhythm of the day is disturbed during the holiday season, some flexibility can be introduced.

It is crucial not to skip doses and not to take two doses at once. Try to maintain a similar pattern every day. It is worth remembering that sertraline has a long half-life (about 26 hours), which means that small fluctuations in the time of intake should not significantly affect the concentration of the drug in the body.

If you have any concerns or concerns about the dosage regimen, it is best to consult with your treating doctor, who can tailor recommendations to your son's individual situation.

Agata  (Anonymous, 89.64.14.) 5 days ago

What is the minimum time interval between taking asertin? My son has a dose of 150 mg, 100 in the morning, 50 in the afternoon.
It's summer holidays and sometimes he gets up at 11-12, I don't know what hours are best, if he takes one day at 9 am and then at 2 pm, and the next day at 12 and then at 3 pm, won't it make a difference?

Anna Pochopień Pharmacist

17 months ago

Yes, unpleasant gastric effects can be triggered by increasing the dose of sertraline. It is a drug that relatively often causes side effects from the gastrointestinal tract. In my opinion, there is no need to reduce the dose – especially if you feel well. One loose stool a day does not pose a health risk, as does shedding in the abdomen. A much greater health risk for you is a dose reduction. Side effects may gradually disappear, but if they worsen or you do not feel any improvement, it would be worth performing gastrological diagnostics. The possibility of online consultation also exists through GdziePoLek: https://www.gdziepolek.pl/telekonsultacja/ I encourage you to read: https://www.gdziepolek.pl/artykuly/jak-i-dlaczego-zglaszac-dzialania-niepozadane https://www.gdziepolek.pl/kategorie/leki-na-depresje https://www.gdziepolek.pl/artykuly/depresja

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