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Can I use Naproxen gel if I cannot take it orally?
Hello, I wanted to ask because the son has diagnosed thrombocytopenia, thrombocytopathy and iron deficiency, the hematologist prescribed only Ferrum, at that time we learned that the son appeared necrosis of the sterile bone knees, the orthopedist said that it was clearly juvenile and recommended rehabilitation, the son has there treatments such as iontophoresis with naproxen, I wanted to ask because the son can not take drugs such as Ibuprom Naproxen orally If they apply topically, how is the degree of this absorption is it safe thank you
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Joanna Dunajska Pharmacist, Editor
18 months ago
Non-steroidal anti-inflammatory drugs in the form of gels or ointments for topical application allow you to achieve analgesic and anti-inflammatory effects, with minimized or no risk of systemic side effects. This form also avoids adverse drug interactions or between drug and disease. Preparations containing non-steroidal anti-inflammatory drugs, e.g. ibuprofen or naproxen, used topically, are absorbed into the bloodstream to a small extent. Naproxen in gel form reaches a very small plasma concentration - 1.1%, accumulates mainly in the epidermis, dermis and muscle tissue. Due to the minimal absorption of the active substance into the body, the risk of systemic side effects is very low when using naproxen locally. In most people who cannot take nonsteroidal anti-inflammatory drugs orally, topical preparations are recommended. The exception are situations in which there is an allergy to a given substance, if my son has one, I would advise against the use of a topical gel. If the doctor recommended the use of Naproxen gel topically and was informed about your son's complaints, please trust his choice. Please also inform the physiotherapist performing the iontophoresis procedure about your son's complaints. I enclose materials that may be useful: https://www.gdziepolek.pl/artykuly/jakie-leki-przeciwbolowe-stosowac https://www.gdziepolek.pl/kategorie/plastry-zele-i-masci-przeciwbolowe