Hello. I take Bicocard 5mg in the morning and Brintellix 10mg for sleep I have Trazodone Neuraxpharm 50mg is it a safe combination of drugs? Can side effects occur if Trazodone stops suddenly?
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Anna Lewandowska Pharmacist, Editor
1 year ago
There are some interactions between the drugs included in the question. The combined use of these medicinal products may be therapeutically beneficial, the patient should be closely monitored for signs of toxicity during the use of the combination. These drugs should be used very carefully under close medical supervision. The use of the drugs Brindelix and Trazodone at the same time can cause an excessive increase in serotonin levels in the brain, which threatens the occurrence of disorders referred to as serotonin syndrome. Serotonin syndrome is manifested, m.in, confusion, agitation, fever, sweating, ataxia, hyperreflexia, muscle clonic seizures and diarrhea. This condition is distinguished by the so-called triad of symptoms, which includes: 1. Vegetative disorders, i.e. increase in blood pressure, fever, diarrhea, vomiting and mydriasis. 2. Psychiatric symptoms, consisting of anxiety disorders, feelings of anxiety and confusion. 3. Neuromuscular complaints, i.e. recurrent cramps, pain and increased muscle tone Therefore, if you observe such side effects, you should inform your doctor, who will decide on this basis what to do. Any modifications in therapy, including discontinuation of the drug, treatment of hypertension or tachycardia should be introduced after consultation with the attending physician acquainted in detail with your state of health: https://www.gdziepolek.pl/artykuly/czy-jak-i-kiedy-mozna-odstawic-leki If you are unable to get to your primary care doctor, the gdziepolek.pl service also allows you to obtain a teleconsultation with a doctor: https://www.gdziepolek.pl/telekonsultacja Avoid abrupt discontinuation of Trazodone. During discontinuation of treatment, the dose should be gradually reduced to minimize the occurrence of withdrawal symptoms in the form of nausea, headache and malaise. The service where polek.pl also allows you to book the medicines listed in the question in the nearest stationary pharmacy upon presentation of the prescription: https://www.gdziepolek.pl/produkty/12147/bisocard-tabletki-powlekane/apteki https://www.gdziepolek.pl/produkty/13859/brintellix-tabletki-powlekane/apteki https://www.gdziepolek.pl/produkty/99760/trazodone-neuraxpharm-tabletki/apteki