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Are there any contraindications to the use of Signopam during therapy with Nebbudem and Pronasal?
Hello, I use inhalations for sinuses steroid drug Nebbud and Pronasal sprayed into the nose. During the illness my insomnia increased and I would like to take Signopam for the night or are there any contraindications? Does such an inhaled drug also metabolize in the liver? As is the case with tablets.
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Anna Lewandowska Pharmacist, Editor
18 months ago
No, there are no contraindications in this case. These drugs do not interact with each other clinically that would preclude their combined use. Signopam can only be obtained with a prescription and should not be used without talking to a specialist. https://www.gdziepolek.pl/produkty/71019/signopam-tabletki/apteki Budesonide (the active substance in Nebbud) is metabolised from the liver. Impaired liver function may affect the elimination of the drug by reducing the rate of elimination and increasing systemic exposure. https://www.gdziepolek.pl/produkty/52516/nebbud-zawiesina/apteki Similarly, Pronasal, a small amount that can be swallowed and absorbed, is metabolized by the liver. https://www.gdziepolek.pl/produkty/64498/pronasal-aerozol/apteki The action and composition of individual drugs can be checked by clicking on the attached links on the gdziepolek.pl website, which also allows you to book them at the nearest pharmacy.