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gość (Anonymous, 78.11.20.) Warszawa 19 months ago

Can I share a tablet of Tamivil?

Hello. The doctor prescribed Tamivil 75 mg to his 10-year-old son with the recommendation to cut and give the child 3/4 tablet. The leaflet states that the medicine must not be divided or chewed. How is it in reality? Should we follow the doctor's instructions or the information in the leaflet?

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Aleksandra Żywiec-Pelczar Pharmacist

19 months ago

According to the official information of the manufacturer, Tamivil tablets should not be divided or crushed. However, the doctor, based on his own knowledge and experience, taking full responsibility for the safety of therapy, has the right to recommend the use of the drug in a manner that deviates from official recommendations. We are talking about the so-called off-label treatment. The summary of product characteristics for Tamivil states: "(...) The available tablet strength is not suitable for the treatment of children weighing less than 40 kg and for doses less than 75 mg. In all of the above cases, and for patients with difficulty swallowing tablets, the availability of oseltamivir in the appropriate dosage and pharmaceutical form should be checked." According to the manufacturer's recommendations, when a dose of less than 75 mg is prescribed, medicinal products containing oseltamivir in a form that allows the administration of the drug in the form of a suspension should be used. This method of administration is allowed for preparations containing oseltamivir capsules, the contents of which can be poured out and a suspension can be prepared, which can be combined with a substance that masks the bitter taste of the drug, e.g. fruit gruel or sugar water. We are talking about the medicinal products Tamiflu and Ebilfumin. Below are the leaflets of these medicinal products, in which you should find the subsection "Preparation of Ebilfumin/Tamiflu" at home: - Ebilfumin: https://www.gdziepolek.pl/produkty/26048/ebilfumin-kapsulki/ulotka/229919 - Tamiflu: https://www.gdziepolek.pl/produkty/77261/tamiflu-kapsulki/ulotka/106732. It is worth knowing that one of the most common side effects observed when administering preparations with oseltamivir (Tamivil. Tamiflu. Ebilfumin) are vomiting. To reduce the risk of their occurrence, the drug should be administered with food. You can read more about off-label treatment in the text: https://www.gdziepolek.pl/artykuly/leczenie-off-label-poza-wskazaniami

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