Is the simultaneous use of paroxetine, quetiapine and risperidone on the recommendation of a doctor really safe? What side effects can occur by combining these substances?
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Anna Lewandowska Pharmacist, Editor
1 year ago
There are some interactions between the medicines included in the question of medicinal products. In general, however, these interactions are not an absolute contraindication to the simultaneous use of these drugs. Paroxetine may increase serum Risperidone concentrations and enhance its effects. Extrapyramidal adverse reactions and isolated cases of serotonin syndrome have been observed during combination therapy. The patient should be monitored for the toxicity of Risperidone and its dosage adjusted if necessary. Risperidone is indicated for short-term treatment (up to 6 weeks). The effects of Paroxetine are usually visible after 10-14 days. If you experience excessive agitation or sedation, muscle stiffness, fever (even over 40 degrees), arrhythmias, excessive sweating or impaired consciousness, contact your doctor. I also encourage you to read the article: https://www.gdziepolek.pl/artykuly/czy-mozna-laczyc-leki-ze-soba