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HtZT (Anonymous, 109.199.1.) Warszawa 1 year ago

Can Ovitrelle be used for a few days after opening?

Good morning. I am on hormone therapy with testosterone + hcg. Due to problems with the availability of Pregnyl, I am forced to use Ovitrelle. Hcg is used in microdoses every 2-3 days after 200-300 iu. The pregnyl pack lasted me for about 2 months and during this period it worked properly. Will using Ovitrelle also be active for a period of 2 months (of course stored in the refrigerator)?

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Aleksandra Żywiec-Pelczar Pharmacist

1 year ago

The Summary of Product Characteristics of Ovitrelle states: "After opening, the preparation should be used immediately. However, it has been shown that after opening, the preparation remains stable for 24 hours provided that it is stored at a temperature of 2° to 8°C.' According to this information, it is impossible to guarantee that the drug will remain active for 2 months. It should be noted, however, that the Pregnyl Summary of Product Characteristics also states that the solution should be administered immediately after mixing the powder with the solvent. The patient should be informed about the details of the dosage of the drug by the doctor conducting the therapy. Perhaps his experience shows that the drug used in a way other than that recommended by the manufacturer remains effective. In case of doubt, I recommend that you consult your doctor again. Finally, I would like to add that a replacement for pregnyl - Eutrig-HP - has appeared on the market. However, according to the Summary of Product Characteristics, the Eutrig-HP solution should be used immediately after reconstitution, i.e. the combination of the powder and the solvent. Below I attach a link with the availability of eutrig-HP: https://www.gdziepolek.pl/produkty/113692/eutrig-hp-iniekcja/apteki/w-polsce

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