When is the best time to use lenzetto? Morning or evening?

The current summary of product characteristics do not specify a specific time of day for the use of the medicine. The daily dose should be administered to adjacent, non-overlapping surfaces measuring 20 cm2, located on the inner side of the forearm between the elbow and wrist. The drug should be allowed to dry for about 2 minutes. The application site should not be washed for 60 minutes. Also, do not allow another person to touch the application site for 60 minutes after administration. Children and animals should not be allowed to come into contact with the area of the forearm on which the medicine has been applied. The results of the studies indicate that the absorption of estradiol is comparable when applied to the skin of the thigh, but decreases when applied to the skin of the abdomen. If the preparation is used according to the instructions, each measured dose delivers the same amount of active substance to the skin, regardless of differences in the shape or appearance of the solution on the skin. For patients who have difficulty applying the prescribed dose to distant, non-overlapping surfaces of the same forearm, the drug can also be applied to the skin of the second forearm or to the inner thigh. No clinically significant difference in the degree of absorption of the drug under the influence of elevated ambient temperature was observed. However, the drug should be used with caution in extreme temperature conditions, such as sunbathing or sauna. When sunscreen was applied 1 h before taking the drug, no effect on absorption was observed. Additional information: https://www.gdziepolek.pl/produkty/89678/lenzetto-aerozol/apteki#stacjonarne https://www.gdziepolek.pl/produkty/89678/lenzetto-aerozol/ulotka/214409