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Beata (Anonymous, 80.238.65.) Warszawa 2 years ago

Can a child vaccinated with Bexsero infect immunocompromised people and is it a live vaccine?

Hello, can a child vaccinated with bexsero infect a child with lowered white blood cells? Is bexsero a live or dead vaccine?

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Angelika Talar-Śpionek Pharmacist, Editor

2 years ago

A child vaccinated with Bexsero does not infect immunocompromised people or other people from his environment. It is not a live vaccine. Bexsero is a protein vaccine developed using reverse vaccinology technology, where proteins that have been shown to be good antigens in the vaccine, i.e. factor H, adhesin A and heparin-binding antigen, have been identified based on the known sequence of the entire genome of meningococcal serogroup B; the vaccine also includes a surface protein prepared by the traditional method. The vaccine works by sensitizing the immune system. When the vaccine is administered, the immune system recognizes the bacterial fragments contained in the vaccine as foreign and produces antibodies against them. After contact of the vaccinated person with bacteria, antibodies along with other components of the immune system will be able to neutralize these bacteria. I enclose a link to information about the drug: https://www.gdziepolek.pl/produkty/10616/bexsero-iniekcja/apteki and materials that may be helpful: https://www.gdziepolek.pl/artykuly/szczepienie-przeciwko-meningokokom The situation you mentioned - that is, the administration of a live vaccine and the infection of immunocompromised people, such as, for example, an intranasal flu vaccine m.in https://www.gdziepolek.pl/produkty/30578/fluenz-tetra-przeciw-grypie-aerozol/apteki

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