For two weeks I took Escitalopram and Trittico, but I feel very bad. Can I go back to my previous medications?

There are certain interactions between the medicinal substances contained in the medicinal products mentioned in the question. The combined use of these drugs may be therapeutically beneficial, the patient should be closely monitored for signs of toxicity during the use of the combination. Concomitant use of Escitalopram with Trittico may result in additive serotonergic effects and/or cardiotoxicity. The occurrence of bradycardia has been reported. What's more, both drugs can cause QT prolongation and torsade de pointes (TdP) tachycardia. These drugs used in patients at risk (female sex, electrolyte disturbances, bradycardia, congenital prolonged QT syndrome, structural heart defects and impaired renal or hepatic function) may increase the risk of developing TdP. Serotonin syndrome is manifested m.in confusion, agitation, fever, sweating, ataxia, hyperreflexia, muscle clonic seizures and diarrhea. This condition is distinguished by the so-called triad of symptoms, which includes: 1. Vegetative disorders, i.e. an increase in blood pressure, fever, diarrhea, vomiting and mydriasis. 2. Psychiatric symptoms, consisting of anxiety disorders, feelings of anxiety and confusion. 3. Neuromuscular ailments, i.e. recurrent cramps, pain and increased muscle tone. These drugs should be used very carefully under strict medical supervision. The ECG should be closely monitored and the patient should be monitored for signs of serotonergic syndrome during parallel use of both drugs. This type of medication should not be discontinued abruptly. The dose should be gradually reduced under medical supervision over a period of at least 1-2 weeks to reduce the risk of withdrawal symptoms. Any modifications in the treatment of difficulties in the area of psychological functioning should be introduced after consultation with the attending physician, who will adjust the treatment according to your current clinical condition.