Dulcobis suppository did not work after 4 hours, could it not dissolve?

The component that forms the suppository mass of the drug Bisacodyl is Vitepsol W 45, which melts at a temperature of 33.5-35.5 degrees Celsius. Melting of the substrate is a physical process, so it is unlikely that the suppository will not melt at the temperature prevailing in the rectum (the temperature prevailing there is about 37 degrees Celsius). Vitepsol W 45 is a substrate species that is characterized by a higher content of monoglycerides (up to 15%), which supports the absorption of active compounds. It is a substrate recommended for laxatives. I enclose additional information: https://www.gdziepolek.pl/artykuly/zaparcia-jak-z-nimi-walczyc