What to do if after 3 days of treatment with Xifaxan and Neomycin, vaginal discharge appeared?

You can start an antifungal treatment now, because it is probably an intimate infection against the background of too much sterilization of the body by the antibiotics used (Xifaxan and Neomycin). As a pharmacist, within my competence, I can offer over-the-counter remedies, for example: Clotidal - vaginal cream with clotrimazole intended for the local treatment of fungal inflammation of the mucous membranes of the genital organs caused by yeast. https://www.gdziepolek.pl/produkty/96042/clotidal-krem-dopochwowy/apteki Lactovaginal - probiotic vaginal capsules used in vaginal discharge and inflammation of the reproductive organs. In addition, the preparation can be taken to supplement or restore the natural bacterial flora in intimate places. https://www.gdziepolek.pl/produkty/42178/lactovaginal-kapsulki-dopochwowe/apteki Trivagin - oral probiotic capsules that allow you to supplement your diet with bacteria of the genus Lactobacillus necessary for the proper functioning of the genitourinary system. In addition, taking the preparation promotes the maintenance of low pH in the intimate areas, which additionally protects against the development of infection. https://www.gdziepolek.pl/produkty/80020/trivagin-kapsulki/apteki I would also consider increasing the dose of the probiotic used, or changing to a stronger preparation. Gastrologists very often recommend Vivomix with such a treatment: https://www.gdziepolek.pl/produkty/89924/vivomixx-proszek-do-wytworzenia-zawiesiny/apteki If possible, I also encourage you to consult a gynecologist who will decide on further proceedings.