Why is perazine antipsychotic at a low dose?

For all, especially long-term used drugs, it is recommended to use the smallest, effective dose. Perazine is considered the drug of first choice for the treatment of m.in delusional syndromes due to its low toxicity and balanced profile of action. Different mechanisms of action, as well as the chemical structure of drugs, make different doses necessary to achieve similar therapeutic effects. Doses of individual neuroleptics should be selected individually by the attending physician. When initiating therapy for acute psychotic disorders, it is recommended to use a dose of perazine between 50 and 150 mg / day. In hospitalized patients, the maximum dose may be up to 800 mg/day. However, for patients treated at home, a maximum dose of up to 300 mg/day is recommended. The mechanism of action of the drug is, m.in, the effect on dopaminergic receptors in the subcortical centers of the brain, hypothalamus and limbic system: https://www.gdziepolek.pl/produkty/60765/pernazinum-tabletki/ulotka/17029 I encourage you to read additional materials that may be useful: https://www.gdziepolek.pl/kategorie/choroby-psychiczne-i-zaburzenia-psychologiczne https://www.gdziepolek.pl/artykuly/jak-zyc-ze-schizofrenia