Do steroids affect TSH?

There have been no interactions between the active ingredients of Metypred and Euthyrox that may adversely affect the safety of their use. It has been proven that glucocorticosteroids (GKS), e.g. metypred, when used orally, can significantly reduce the concentration of TSH in the blood. However, their effect on the concentration of thyroid hormones has not been proven. The effect of this therapy on the concentration of TSH is reversible, with the end of treatment, the level of TSH should return to the level before the start of GKS therapy. I would like to add that in people with hypothyroidism, the effect of methyprednisolone contained in Metypred may be stronger, hence in these patients it may be necessary to reduce the dose. Tell your doctor who recommends Metypred that you have hypothyroidism (if any) before starting treatment. I encourage you to read the article: https://www.gdziepolek.pl/artykuly/10-najczestszych-bledow-w-przyjmowaniu-lekow