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Bella (Anonymous, 89.64.100.) Warszawa 2 years ago

With which analgesics can methotrexate be combined?

-Which analgesic/antipyretic medicine is best used with methotrexate(RA)? -Will the use of paracetomol in suppositories be safer than paracetamol in tablets? -Is the use of ibuprofen in suppositories as indicated as in tablets?

ApapIbupromMethotrexatMetotreksatBólWhat painkillers to use?
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Angelika Talar-Śpionek Pharmacist, Editor

2 years ago

Methotrexate can be combined with drugs containing paracetamol. Both forms of paracetamol - both tablets and suppositories are a safe form of treatment. Suppositories act faster, this form of administration of the drug allows you to bypass the gastrointestinal tract and portal circulation of the liver, so that the drug does not irritate the stomach. Thus, this may speak in favor of the use of suppositories in this situation. Administration of ibuprofen - both in the form of suppositories and tablets is inadvisable in this case. I attach a link to a similar post on combining methotrexate with painkillers: https://www.gdziepolek.pl/opinie-i-pytania/43504/apap-jakie-leki-przeciwbolowe-mozna-przyjmowac-podczas-stosowania-metotabu

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