Whether Reseligo can result in water retention in the body? Can this condition persist throughout the entire period of taking the drug?

The Package Leaflet and the Summary of Product Characteristics for Reseligo do not describe the adverse reaction of water retention. However, weight gain that may have been associated with this has been commonly observed in patients.

The active substance of the drug, goserelin, is a synthetic analogue of gonadotropin-releasing hormone, which, when administered over a long period of time, results in the inhibition of luteinizing hormone (LH) secretion by the pituitary gland, leading to a decrease in serum testosterone levels in men and a decrease in serum estradiol levels in women. However, goserelin may transiently increase serum testosterone in men and serum estradiol in women at the beginning of treatment, which may contribute to increased water retention and oedema, resulting in weight gain. The observed symptoms - if they are related to the use of Reseligo - should therefore disappear over time.

Because each body responds differently to treatment, the symptoms you see may or may not necessarily be related to the use of the drug. Useful information on water retention in the body, along with other causes of this condition, can be found in the article on our website:

https://www.gdziepolek.pl/artykuly/fakty-i-mity-o-zatrzymaniu-wody-w-organizmie

If you have any doubts about your treatment, I encourage you to consult a doctor on the Gdziepolek.pl portal:

https://www.gdziepolek.pl/telekonsultacja

Observed side effects should be reported to the doctor, but also individually. We wrote about how and why it is worth doing it here:

https://www.gdziepolek.pl/artykuly/jak-i-dlaczego-zglaszac-dzialania-niepozadane

Here you can check the availability of your medication and make a reservation at the pharmacy:

https://www.gdziepolek.pl/produkty/91019/reseligo-iniekcja/apteki