Can amitriptyline and propranolol cause stiff legs and tingling, as well as migraines with aura?
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Klaudia Ćwiąkała Pharmacist, Editor
26 days ago
Amitriptyline often (up to 1 in 10 patients) causes paresthesia, which is manifested by unusual sensation in the limbs - tingling, numbness, stinging, a feeling of heat, sometimes burning, and even a feeling of running electricity. Amitriptyline is used in the prevention of migraine, i.e. it reduces the frequency of migraine attacks.
Propranolol rarely causes paresthesia and is also used in the prevention of migraine.
If you associate the occurrence of the described effects with taking medications, you should report it. Reporting side effects allows you to gather more information about the safety of medicines and update data on them, which can help other patients in the future. We wrote about how to report them here: https://www.gdziepolek.pl/artykuly/jak-i-dlaczego-zglaszac-dzialania-niepozadane
Adverse drug reactions can also be reported individually: https://www.urpl.gov.pl/pl/produkty-lecznicze/monitorowanie-bezpieczeństwa-leków/zg moose-side-effect-0
I attach other helpful studies:
https://www.gdziepolek.pl/artykuly/czy-bac-sie-dzialan-niepozadanych-lekow