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Non-prescription medicines delivery across Europe.
Frequently ordered: potency boosters (sildenafil OTC), quit smoking aids.
Can Coroswere be used with milk thistle?
Hello, can I take milk thistle when using coroswera 40+10 mg due to increased ALT levels? Milk thistle can reportedly cause an increase in statin hepatoxicity.
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Joanna Dunajska Pharmacist, Editor
5 months ago
Milk thistle may have properties that inhibit the action of the isoenzyme CYP 3A4 responsible for the metabolism of many drugs. Corosaver contains two active substances, rosuvastatin and ezetimibe.
Rosuvastatin is metabolised primarily by CYP2C9 and to a lesser extent by CYP 3A4.
According to the Summary of Product Characteristics, there were no clinically relevant interactions with rosuvastatin and CYP 3A4 inhibitors.
Milk thistle may exacerbate the side effects of statins, those that are mainly metabolised by the CYP 3A4 isoenzyme, e.g. atorvastatin.
Here you can compare the prices of preparations containing milk thistle, book them or order them with delivery:
https://www.gdziepolek.pl/substancje/ostropest-plamisty
You can also book prescription medications at a pharmacy of your choice through Gdziepolek:
https://www.gdziepolek.pl/produkty/99347/coroswera-40-mg-10-mg-tabletki-powlekane/apteki
I encourage you to familiarize yourself with the helpful materials:
https://www.gdziepolek.pl/artykuly/czy-mozna-laczyc-leki-ze-soba