Does Forxiga affect the heart?

Forxiga may be used to benefit patients with certain heart conditions - specifically heart failure. The exact reimbursement indication for Forxiga is as follows: chronic heart failure in adult patients with reduced left ventricular ejection fraction (LVEF≤40%) and persistent symptoms of disease in NYHA class II-IV despite the use of therapy based on ACEi (or ARB / ARNi) and drugs from the group of beta-blockers and if indicated mineralocorticoid receptor antagonists. Dapagliflozin - the active ingredient in Forxiga - causes glucose excretion in the urine, which is the basis of its use in diabetes. However, in fact, the drug also has other effects that can be beneficial in case of heart failure - by affecting various processes occurring in the kidneys, the load on the left ventricle of the heart is reduced. In addition, there is also an improvement in myocardial metabolism, a beneficial effect on cardiac remodeling and the preservation of kidney function. I enclose additional information about Forxiga: https://www.gdziepolek.pl/produkty/92331/forxiga-tabletki-powlekane/apteki and our studies that may be helpful: https://www.gdziepolek.pl/artykuly/ile-kosztuje-zycie-z-cukrzyca https://www.gdziepolek.pl/kategorie/leki-na-niewydolnosc-serca