Good morning: Will flunarizine-induced depression pass after discontinuation of the drug and if so, after what time?
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Joanna Dunajska Pharmacist, Editor
14 months ago
There is no precise time after which the depression caused by flunarizine will pass. Given that the cause is only the presence of the substance in the body, it can be suggested that after the elimination of flunarizine, the side effect will pass. It is believed that the total elimination time of the drug from the body is about 5 half-life of the substance. For flunarizine used chronically at a dose of 10 mg, the half-life is about 19 days. The results are that complete elimination should take place after about 95 days. It is also possible that with a gradually decreasing concentration of the substance, the symptoms of depression will pass earlier.10 I enclose information about the possibility of using teleconsultation, if necessary: https://www.gdziepolek.pl/telekonsultacja and materials on reporting adverse reactions: https://www.gdziepolek.pl/artykuly/jak-i-dlaczego-zglaszac-dzialania-niepozadane