Can very loud growling, overflow in the stomach after a meal be related to Axotret?

Thank you for sharing your case. According to the Summary of Product Characteristics, gastrointestinal disorders are a very rare side effect of Axotret: https://www.gdziepolek.pl/produkty/8353/axotret-kapsulki/apteki Gurgling in the belly, overflow in the intestines and loud, constant growling can have many causes. Usually, these symptoms are related to the body's natural reaction before eating. The feeling of overflowing water in the abdomen after a meal associated with the mixing of food content with acids in the stomach. In addition, the cause of bubbling and rumbling in the abdomen may be gases in the intestines, which during natural contractions (so-called bowel movements) make unwanted noises – embarrassing, loud sounds. The feeling of overflow can also be associated with indigestion and eating unhealthy foods, then the symptoms are accompanied by stomach pain and bloating. If the symptoms last for a long time and are the cause of discomfort, they should be consulted with a doctor to determine the cause and make a diagnosis. If you want to improve digestive comfort during Axotret treatment, it is worth reaching for a good probiotic, which will not only improve digestion, but also support the regeneration of intestinal microflora, e.g.: Sanprobi Barrier: https://www.gdziepolek.pl/produkty/95137/sanprobi-barrier-kapsulki/apteki The action and composition of individual drugs can be checked by clicking on the attached links on the GdziePoLek.pl website, which also allows you to book them in a selected pharmacy.