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Milva (Anonymous, 91.192.199.) Polska 16 months ago

Can I use Ovitrelle if the pen has been away from the fridge for 2 days?

In the leaflet of the syringe it says that if the medicine is used within 30 days, it can be stored outside the refrigerator at a temperature of up to 25 degrees. However, in the pen leaflet it says to keep between 2 and 8 degrees and there is nothing about these 30 days. Where does this difference come from, since it is the same substance? Can I safely use the medicine I have in my pen if it has been outside the fridge for 2 days?

5 answers, 1 subscriber

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Anna Lewandowska Pharmacist, Editor

17 days ago

To @Justyna:

Gonapeptyl, like many other injectable medications, should be refrigerated, but it is a good idea to remove it to bring it to room temperature before administering it. This can increase the patient's comfort during the injection. It is advisable to take the ampoule out of the refrigerator about 30 minutes before the scheduled injection.

If you don't feel uncomfortable giving Gonapeptyl straight from the refrigerator, there's probably no need to change your current practice. However, if you feel that the injection is uncomfortably cold or uncomfortable, you may want to consider taking the medicine out of the fridge for a short time before administration (e.g. 15-30 minutes) or warming it in your hands.

Justyna (Anonymous, 62.45.37.) 17 days ago

Should I take gonapeptyl out of the fridge earlier before administration, because I have already done 5 injections straight from the fridge and I don't know if I should take it out before or not

Angelika Talar-Śpionek Pharmacist, Editor

15 months ago

If the medicine has not been opened, it can be stored outside the refrigerator for 30 days, e.g. in the pharmacy the drug is stored in the refrigerator, however, after its release from the pharmacy, the patient can store the medicine at home at room temperature - but not longer than 30 days. "Ovitrelle 250 micrograms solution for injection can be stored at room temperature (below 25°C) for up to 30 days without the need for re-cooling during this time. The solution should be discarded if it has not been used within these 30 days.'

Milva (Anonymous, 91.192.199.) 15 months ago

Thank you for your reply. However, the pen is still closed, it has not been opened in any way. Is it still not possible to use it in such a situation?

Anna Lewandowska Pharmacist, Editor

15 months ago

No, you should not use Ovitrelle if stored outside the refrigerator. In the Summary of Product Characteristics of Ovitrelle, the manufacturer states that after opening, the preparation should be used immediately. The preparation remains stable for 24 hours provided that it is stored at a temperature of 2° to 8°C. The pen and the pre-filled syringe are not identical products. I enclose materials that may be interesting and information about the possibility of using teleconsultation: https://www.gdziepolek.pl/telekonsultacja https://www.gdziepolek.pl/artykuly/wspomaganie-plodnosci The GdziePoLek.pl service also allows you to book Ovitrelle in the nearest stationary pharmacy and pick up after presenting the prescription: https://www.gdziepolek.pl/produkty/58329/ovitrelle-iniekcja/apteki

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